Alexander Zarbock | Research Committee member
The Clinical Trial Network reception of the ESA was organised on Sunday, 31 May 2015 at the City Cube in Berlin, Germany during Euroanaesthesia 2015.
Prof. Wolfgang Buhre, the new Chairperson of the Research Committee, welcomed all participants and emphasized the importance of the Clinical Trial Network. He highlighted that this programme is intended to provide the infrastructure for institutions, clinicians and scientists to work collaboratively across international borders to improve the care of patients in the field of anaesthesiology, intensive care, peri-operative medicine, emergency medicine and pain medicine. Prof. Buhre congratulated the chief investigators and co-authors of the multi-centre studies that have been completed and led to publications in high impact journals such as the Lancet (EuSOS) and Anesthesiology (PERISCOPE). He also mentioned that several other studies have been completed and that the results will be published soon (LAS VEGAS, euCPSP PAIN OUT, ETPOS, and OBTAIN).
Prof. Buhre invited Dr. Nicola Disma (Istituto Giannina Gaslini, Italy) to say a few words about the NECTARINE (Neonate-Children audit of Anaesthesia pRactice IN Europe) study, a prospective multi-center observational study on the epidemiology of morbidity and mortality in neonatal anesthesia. The primary outcome of the study is to investigate the medical interventions and/or treatments for critical events during and after anaesthesia. The investigators anticipate that 200 European centres will be needed to recruit at least 5000 patients. The investigators invited the attendees to participate and support the study.
Subsequently, Prof. Buhre passed the word to Prof. Anil Gupta (Stockholm, Sweden), the chief investigator of the EPiMAP Obstetrics (European Practices In the Management of Accidental dural Puncture in Obstetrics). In this trial, the authors try to identify the risk factors for failed epidural blood patch following post-dural puncture headache. The recruitment period will start on 1 January 2016, and will end in December 2016. In this time period, more than 1024 patients in approximately 200 centres should be recruited.
Then Prof. Buhre called on stage Prof. Marcelo Gama de Abreu (Dresden, Germany) – chief investigator of the PROBESE (Protective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in Obese Patients) trial. Prof. Gama de Abreu and colleagues try to recruit 748 patients to investigate whether higher PEEP levels and recruitment maneuvers during surgery can reduce postoperative pulmonary complications in obese patients.
Dr. Philipp Lirk (Amsterdam, Netherlands) presented the PLATA (Prevention of Phantom Limb Pain After Transtibial Amputation) trial. The investigators of this study compare optimized pain control versus optimized pain control plus a nerve block. The aim is to recruit 400 patients at 15 centres.
Finally, Prof. Buhre warmly encouraged all attendees to take part in trials organised by the CTN programme of the ESA.
Last but not least, Prof. Wolfgang Buhre warmly thanked the CTN team in Brussels, namely Sandrine Damster, Brigitte Leva, Pierre Harlet and Benoît Plichon who are doing a fantastic job in helping and coaching the local and national coordinators of all the studies that are underway or in preparation.
This CTN reception was – as always – a good opportunity to meet and get to know colleagues. All participants look forward to the next CTN reception at Euroanaesthesia 2016 in London, United Kingdom!
From left to right: Paolo Pelosi, Research Committee Chair 2006-2009, Wolfgang Buhre, current Research Committee Chair, Andreas Hoeft, Research Committee chair 2010-2015
Join an ESA Clinical Trial Network study!
• PLATA: Prevention of Phantom Limb Pain After Transtibial Amputation: Randomized, double-blind, controlled, multi-center trial comparing Optimized pain control vs Optimized pain control plus Nerve Block Interventional study Chief Investigator: Philipp Lirk (Netherlands) (study ongoing – protocol available)
• NECTARINE: NEonate-Children audiT of Anaesthesia pRactice IN Europe Epidemiology of morbidity and mortality in neonatal anaesthesia: A European prospective multicentre observational study. Chief Investigator Nicola Disma (Italy) (study planned for 2016-no protocol available yet)
• EPiMAP Obstetrics: European Practices in the Management of Accidental dural Puncture in Obstetrics Observational study. Chief Investigator Anil Gupta (Sweden) (study planned for 2016-no protocol available yet)
• PROBESE: PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients – The PROBESE Randomized Controlled Trial. Chief Investigator Marcelo Gama de Abreu (Germany) (study ongoing-protocol available)
If you are interested please do not hesitate complete the Online Call for Centres Form to facilitate coordination and confirm your Institution’s participation in an ESA CTN study.